Real-time outbreak analysis: Ebola as a case study - part 1

#simulation #response #ebola #epicurve #reproduction number

Introduction This practical (in three parts) simulates the early assessment and reconstruction of an Ebola Virus Disease (EVD) outbreak. It introduces various aspects of analysis of the early stage of an outbreak, including case fatality ratio (CFR), epicurves (part 1), growth rate estimation, contact tracing data, delays, and estimates of transmissibility (part 2), as well as transmission chain reconstruction using outbreaker2 (part 3). Note: This practical is derived from earlier practicals called Ebola simulation part 1: early outbreak assessment and Ebola simulation part 2: outbreak reconstruction ...

An outbreak of gastroenteritis in Stegen, Germany, June 1998

You are using an outdated browser. Please upgrade your browser or activate Google Chrome Frame to improve your experience. Context On 26 June 1998, the St Sebastian High School in Stegen (school A), Germany, celebrated a graduation party, where 250 to 350 participants were expected. Attendants included graduates from that school, their families and friends, teachers, 12th grade students, and some graduates from a nearby school (school B). ...

Ebola simulation part 2: outbreak reconstruction

#genetics #simulation #response #outbreaker2 #epicurve #reproduction number #ebola

This practical is the second part of the response to a simulated Ebola Virus Disease (EVD) outbreak taking place in the city of Ankh, Republic of Morporkia. While the first part focussed on early assessments of transmissibility, this part explores more methodological options for estimating transmissibility, and provides an introduction to outbreak reconstruction using outbreaker2. An update on the EVD outbreak in Ankh, Republic of Morporkia After some rather concerning preliminary results on the new EVD outbreak in the city of Ankh, Republic of Morporkia, Public Health Morporkia (PHM) has sent you updates of the linelists and contact data. ...

Introduction to phylogenetics

#genetics #evolution

This lecture introduces general concepts pertaining to phylogenetic tree reconstruction, as well as the main approaches used for building trees, including distance-based, maximum parsimony, and maximum likelihood methods. It also discusses phylogenetic uncertainty, bootstrap, and some caveats and bad practices. Slides Click on the image below to access the slides: About this document Contributors Thibaut Jombart: initial version Contributions are welcome via pull requests. The source files of this lecture can be found here. ...

Outbreak investigation using outbreaker2

#reconstruction #outbreaker2

This short lecture gives a primer on some methodological aspects of outbreak reconstruction using outbreaker2. Slides Click on the image below to access the slides: About this document Contributors Thibaut Jombart: initial version Finlay Campbell: figure on *outbreaker2*’s contact model Contributions are welcome via pull requests. The source file can be found here. Legal stuff License: CC-BY Copyright: Thibaut Jombart, 2017