TB: exploring the case of TB elimination with a simple compartmental model

#tuberculosis

Eliminating tuberculosis (TB) is now a priority in the Global Health agenda. Is it achievable? How and when could this happen? Though still uncertain, it is an ongoing discussion in the field. In this practical, we will illustrate important concepts of TB epidemiology with a simple compartmental model and assess the interventions required to achieve elimination thresholds and End TB goals set by the World Health Organization (WHO). Core concepts The following concepts will be developed during the practical: ...

Real-time outbreak analysis: Ebola as a case study - part 3

#simulation #response #ebola #epicurve #reproduction number

Introduction This practical is the third (and last) part of a practical which simulates the early assessment and reconstruction of an Ebola Virus Disease (EVD) outbreak. Please make sure you have gone through part 1 and part 2 before starting part 3. In part 3 of the practical, we give an introduction to transmission chain reconstruction using outbreaker2. Note: This practical is derived from earlier practicals called Ebola simulation part 1: early outbreak assessment and Ebola simulation part 2: outbreak reconstruction ...

Real-time outbreak analysis: Ebola as a case study - part 2

#simulation #response #ebola #epicurve #reproduction number

Introduction This practical is the second (out of three) part of a practical which simulates the early assessment and reconstruction of an Ebola Virus Disease (EVD) outbreak. Please make sure you have gone through part 1 before starting part 2. In part 2 of the practical, we introduce various aspects of analysis of the early stage of an outbreak, including growth rate estimation, contact tracing data, delays, and estimates of transmissibility. ...

Real-time outbreak analysis: Ebola as a case study - part 1

#simulation #response #ebola #epicurve #reproduction number

Introduction This practical (in three parts) simulates the early assessment and reconstruction of an Ebola Virus Disease (EVD) outbreak. It introduces various aspects of analysis of the early stage of an outbreak, including case fatality ratio (CFR), epicurves (part 1), growth rate estimation, contact tracing data, delays, and estimates of transmissibility (part 2), as well as transmission chain reconstruction using outbreaker2 (part 3). Note: This practical is derived from earlier practicals called Ebola simulation part 1: early outbreak assessment and Ebola simulation part 2: outbreak reconstruction ...

VBD: building a simple model for Zika

#zika #compartmental models

This practical aims to illustrate the basics of vector borne disease (VBD) modelling using R, with an emphasis on how the methods work. We will use a basic model for an arboviral infection as an example. In this practical we will begin by gaining some understanding of the components which contribute to $R_0$ and how potential interventions influence transmission. Later in the practical you will construct a model of Zika transmission to look at the effects of several parameters. ...