Real-time outbreak analysis: Ebola as a case study - part 3

#simulation #response #ebola #epicurve #reproduction number

Introduction This practical is the third (and last) part of a practical which simulates the early assessment and reconstruction of an Ebola Virus Disease (EVD) outbreak. Please make sure you have gone through part 1 and part 2 before starting part 3. In part 3 of the practical, we give an introduction to transmission chain reconstruction using outbreaker2. Note: This practical is derived from earlier practicals called Ebola simulation part 1: early outbreak assessment and Ebola simulation part 2: outbreak reconstruction ...

Real-time outbreak analysis: Ebola as a case study - part 2

#simulation #response #ebola #epicurve #reproduction number

Introduction This practical is the second (out of three) part of a practical which simulates the early assessment and reconstruction of an Ebola Virus Disease (EVD) outbreak. Please make sure you have gone through part 1 before starting part 2. In part 2 of the practical, we introduce various aspects of analysis of the early stage of an outbreak, including growth rate estimation, contact tracing data, delays, and estimates of transmissibility. ...

Real-time outbreak analysis: Ebola as a case study - part 1

#simulation #response #ebola #epicurve #reproduction number

Introduction This practical (in three parts) simulates the early assessment and reconstruction of an Ebola Virus Disease (EVD) outbreak. It introduces various aspects of analysis of the early stage of an outbreak, including case fatality ratio (CFR), epicurves (part 1), growth rate estimation, contact tracing data, delays, and estimates of transmissibility (part 2), as well as transmission chain reconstruction using outbreaker2 (part 3). Note: This practical is derived from earlier practicals called Ebola simulation part 1: early outbreak assessment and Ebola simulation part 2: outbreak reconstruction ...

A primer on statistical outbreak analysis

#epicurve #delays #reproduction number #forecasting

This short lecture gives a primer on some methodological aspects of outbreak analysis. It includes content on the estimation of key delays (e.g. incubation period, serial interval) and the characterisation of the underlying distributions, the estimation of growth rates, doubling times, of the basic reproduction number and simple short-term forecasting. Slides Click on the image below to access the slides: About this document Contributors Thibaut Jombart: initial version Contributions are welcome via pull requests. ...

Ebola simulation part 1: early outbreak assessment

#simulation #response #ebola #epicurve #reproduction number

This practical simulates the early assessment and reconstruction of an Ebola Virus Disease (EVD) outbreak. It introduces various aspects of analysis of the early stage of an outbreak, including contact tracing data, epicurves, growth rate estimation from log-linear models, and more refined estimates of transmissibility. A follow-up practical will provide an introduction to transmission chain reconstruction using outbreaker2. A novel EVD outbreak in Ankh, Republic of Morporkia A new EVD outbreak has been notified in the small city of Ankh, located in the Northern, rural district of the Republic of Morporkia. ...

Is this outbreak over?

#epicurve #outbreak #outbreak end

Motivation At which time point during an outbreak of a person-to-person transmitted disease can one declare the outbreak as having ended? Answering this question can be important in order to calm the population, re-attract tourists, stop export bans or reduce alertness status. The current WHO method for answering the above question is as follows: a period of two times the longest possible incubation time needs to pass without observing additional cases, before the outbreak can be declared as being over. ...

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